Author: Journal Of Venomous Animals And Toxins Including Tropical Diseases

Snake venom toxin activates immune cells and decreases the invasion potential of tumor cells

BJcuL toxin – isolated from the venom of the Brazilian snake Bothrops jararacussu – was able to stimulate cells of the immune system to act against tumor cells. Blood neutrophils, when stimulated by BJcuL, reduced the migratory potential of neuroblastoma cells in culture. Read More →

Treatment of difficult-to-heal venous ulcers with fibrin sealant

Difficult-to-heal ulcers in lower limbs are those that occur below the knee and for several reasons do not reach healing, remaining open for months or years. Difficulties in healing encourage the development of new products. Fibrin sealant is one of these alternatives because it is a biological dressing with excellent healing properties. Read More →

Bufotenine and new perspectives for the treatment of rabies

Currently, rabies remains almost 100% fatal due to the lack of specific treatment. Bufotenine – an alkaloid present in some frogs’ skin secretions as well as in plant seeds – has been shown to be effective in reducing either the onset of symptoms or the mortality in mice. Read More →

How can the use of a biological glue allow motor recovery after spinal cord injury?

Upper and lower limb injuries are common outcomes of accidents. There is no significant recovery and surgical options are quite limited. A research has developed a new therapy by using the fibrina sealant produced by the Center for the Study of Venoms and Venomous Animals (CEVAP) conjugated with the drug dimethyl fumarate. The results are encouraging regarding mobility recovery. Read More →