Category: Health Sciences

Cameras and monitors improves experimental surgeries for correcting incisional hernia in rats

Horizontal rectangular photo. An oval cut in the skin of a mouse. It is possible to see inside the opening a mesh reminiscent of metal, the skin cut around the cut is red and almost translucent, the pinkish skin of the mouse with small spots and some white hairs around the part shaved for the cut. Surrounding the image is an opaque blue background.

The use of cameras and screens in surgical procedures with Wistar rats has demonstrated efficacy and high performance. The 50x magnified visualization with a low-cost system circumvents one of the main difficulties of experimental studies, enabling further research with biocompatible models that generate more accurate results. Read More →

More benefits, fewer risks: Tranexamic acid reduces bleeding and prevents complications in laparoscopic bariatric surgery

Flowchart of the patient analysis in English. At recruitment, starting from the total number of patients (62), 1 was excluded, 0 did not meet the criteria, 0 refused to participate. Allocation: starting from "Control - non-randomized (61)" comes out two arrows forming two horizontal columns. First column: allocated to control group (31), received tranexamic acid (0), follow-up (31), analysis (31). Second column allocated to the group that received tranexamic acid (30), received tranexamic acid (30), follow-up (30), analysis (30).

Medicine’s accessibility, easy administration protocol and absence of thrombogenic adversities indicate that tranexamic acid is a safe and low-cost strategy, applicable to all phases of laparoscopic sleeve gastrectomy surgery, optimizing recovery and reducing hospital stay of patients. Read More →

InsulinAPP application is effective and safe for the management of hyperglycemia on a hospitalist-managed ward

Imagem retangular na horizontal. Uma mão segurando um celular e a outra mão apontando para a tela. Na tela do celular um gradiente azul. No fundo círculos brancos e linhas tracejadas coloridas (azul, verde, amarelo, laranja, vermelho).

This retrospective study assessed metrics related to inpatient glycemic control using InsulinAPP, an application available for free in Brazil, on the hospitalist-managed ward of a local institution. The results indicated that the InsulinAPP using human insulin formulations was effective and safe for the management of hyperglycemia in this setting. Read More →

Substance present in turmeric may be a new therapeutic option in the treatment of ulcerative colitis

In an evaluation of the colon tissue of rats with induced ulcerative colitis, the use of curcumin, a substance present in turmeric, contributed to the reduction of the inflammatory process. The results reveal an optimistic outlook for the application of curcumin and its potential as a pharmaceutical product. Read More →

Viral clockworks: How do coronaviruses spill over?

Composition in rectangular format. Deep yellow background, an orange virus occupies half of the picture. The virus has white hands and feet and stands on a black clock with white details.

Coronaviruses are widespread in mammals and birds and sometimes they jump species, as SARS-CoV-2 from bats to humans. This investigation describes the genomic events during Avian coronavirus passages from hamster cells to primate cells in order to understand the mechanisms of coronavirus adaptation to a new host. Read More →

Sarcopenia prevalence did not increase in women undergoing gastric bypass despite weight loss

Graphic with number of patients with sarcopenia parameters in the bariatric and control groups (A) and in bariatric and control groups based on sarcopenia diagnosis (B)

Women (18-65 years old) who underwent bariatric surgery (BG) ≥ 2 years and reached stable weight ≥ 6 months, were investigated in an observational, cross-sectional study for sarcopenia’s presence. Patients subjected to Roux-en-Y gastric bypass did not show increased sarcopenia prevalence in comparison to non-operated women with obesity, despite the significant weight loss. Read More →

Sequencing of the first case of the monkeypox virus in Brazil

Genome sequencing of the B.1 lineage

Monkeypox virus, a zoonotic virus endemic to the African continent, has been reported in 33 non-endemic countries since May 2022. We report an almost complete genome of the first confirmed case of MPXV in Brazil. Shotgun metagenomic sequencing was completed in 18 hours, from DNA extraction to consensus sequence generation. Read More →

Impact of semioccluded vocal tract exercises and choral singing in congenital GH deficiency’s subjects

Photograph of a microphone on a dark background.

Isolated growth hormone deficiency (IGHD) individuals report normal general quality of life but rate their Voice-Related Quality of Life (V-RQOL) as low. Voice therapy with semioccluded vocal tract exercises and choral training can markedly improve V-RQOL scores, voice self-assessment and auditory-perceptual analysis in IGHD subjects, although GH replacement therapy is not widely accepted. Read More →

CEVAP: ready for the 21st century

CEVAP has been working diligently since its founding in translational research with animal venoms. During this 30-year journey, a scientific journal was launched, two biopharmaceuticals were developed and numerous professionals, academic or not, were trained. Now, CEVAP is heading towards its future looking towards the creation of a factory aiming at scientific research. Read More →

Memorial text in honor of Dr. Ángela Restrepo Moreno

An example of competence, researchers education, ability to work in group, and also love to her profession, her team and her country, Dr. Ángela Restrepo Moreno will be forever missed. The present text aims honor the memory and accomplishments of this extraordinary researcher, whose contribution to science is immortalized. Read More →