The increase in the prevalence of type 2 diabetes and metabolic syndrome in children and adolescents is a health concern. Therefore, a valid and accessible method of assessing insulin resistance in this age group must be developed to monitor its progression and identifying adolescents at risk of developing associated factors. … Read More →
Epidemiology and risk factors of hypoglycemia in type 1 diabetes in Brazil
Factors associated with hypoglycemia and severe hypoglycemia (SH) in individuals with type 1 diabetes mellitus (T1D) in Brazil shows that avoiding high doses of basal insulin and educating individuals about alcohol consumption and its consequence on glycemic control are simple measures that can contribute to reducing SH events. … Read More →
Trabecular bone score and its evolving role in the assessment and management of clinical conditions
Trabecular bone score (TBS) is a noninvasive measure of bone quality. A low TBS indicates degraded bone microarchitecture, predicts osteoporotic fracture, and is partially independent of clinical risk factors and bone mineral density. Today TBS has an evolving role in the assessment and management of several clinical conditions. … Read More →
InsulinAPP application is effective and safe for the management of hyperglycemia on a hospitalist-managed ward
This retrospective study assessed metrics related to inpatient glycemic control using InsulinAPP, an application available for free in Brazil, on the hospitalist-managed ward of a local institution. The results indicated that the InsulinAPP using human insulin formulations was effective and safe for the management of hyperglycemia in this setting. … Read More →
Sarcopenia prevalence did not increase in women undergoing gastric bypass despite weight loss
Women (18-65 years old) who underwent bariatric surgery (BG) ≥ 2 years and reached stable weight ≥ 6 months, were investigated in an observational, cross-sectional study for sarcopenia’s presence. Patients subjected to Roux-en-Y gastric bypass did not show increased sarcopenia prevalence in comparison to non-operated women with obesity, despite the significant weight loss. … Read More →
Impact of semioccluded vocal tract exercises and choral singing in congenital GH deficiency’s subjects
Isolated growth hormone deficiency (IGHD) individuals report normal general quality of life but rate their Voice-Related Quality of Life (V-RQOL) as low. Voice therapy with semioccluded vocal tract exercises and choral training can markedly improve V-RQOL scores, voice self-assessment and auditory-perceptual analysis in IGHD subjects, although GH replacement therapy is not widely accepted. … Read More →
Brazilian Medical Societies propose a new obesity classification based on weight history
In the new obesity classification, individuals losing a specific proportion of weight are classified as having “reduced” or “controlled” obesity. This classification could help disseminate the concept of clinical benefits derived from modest weight loss, allowing subjects with obesity and their health care professionals to focus on strategies for weight maintenance instead of further weight reduction. … Read More →
Canagliflozin seems to be more potent in reducing glycated hemoglobinand and body weight in patients with type 2 diabetes
Among the different doses of gliflozins commercially available in Brazil, Canagliflozin 300 mg had the greatest benefit in terms of body weight reduction, however, results were not different from empagliflozin 25 mg and dapagliflozin 10 mg. It’s not worthwhile to increase gliflozins doses with the intent to further decrease glycated hemoglobin or body weight. … Read More →
The prognosis of differentiated thyroid cancer is not affected by pregnancy
Pregnancy had no impact on the natural course of differentiated thyroid cancer. Disease progression after pregnancy was limited and probably related to more aggressive disease and higher risk stratification at diagnosis. Still, mild disease progression may have occurred asymptomatically in some patients. … Read More →
Multifocality and LN metastasis are independent risk factors for incomplete response in TMC patients
This was a retrospective study that aimed at identifying possible risk factors associated with an incomplete response to therapy in thyroid microcarcinoma (TMC) treated with total thyroidectomy, with or without radioactive iodine (RAI) therapy, reclassified according to the response to treatment into “favorable” (excellent/indeterminate) or “unfavorable” (biochemical/structural incomplete) responses. … Read More →
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