Category: Health Sciences

Predictive factors for permanent congenital hypothyroidism was shown by a real-life study in Brazil

Photo: A doctor is holding a baby on an office table. She is smiling and looking at the baby. Baby looks at the camera and seems to bite a finger.

Congenital hypothyroidism can be permanent (PCH) or transient. A real-life retrospective trial aimed to determine predictive factors for PCH and verify its prevalence changes over time. It discovered the most important PCH predictors are the initial thyroid-stimulating hormone serum (TSH) and the blood spot TSH. Read More →

Homeostasis model assessment is negatively associated with the clamp-derived insulin sensitivity index in adolescents

Photo: a hand holding a glucose meter and pointing to a finger of the other hand. In the background, a glucose monitor.

The increase in the prevalence of type 2 diabetes and metabolic syndrome in children and adolescents is a health concern. Therefore, a valid and accessible method of assessing insulin resistance in this age group must be developed to monitor its progression and identifying adolescents at risk of developing associated factors. Read More →

HPV infection may not be responsible for prostate cancer, but it’s better to prevent

Photo of a man lying on a hospital equipment. Two health professionals are beside him. A metal plate is over the man's body.

Since effective vaccines against HPV already exist, understanding the dynamics between papillomavirus and prostate cancer is relevant because it can contribute to the development of strategies for prevention and early diagnosis, although prospective analysis does not clearly demonstrate a relationship. Read More →

Improvements in colonoscopy performance help prevent and treat colorectal cancer

Composition: photo of a person lying down being seen by three health professionals. Blue frame in the upper left corner with the text "Quality indicators in colonoscopy: Observational study in a supplementary health system" and link.

Colonoscopy plays an essential role in detecting and diagnosing lesions and tumors of the colorectal mucosa. The quality of the equipment used, the colonoscopist’s technical knowledge and practical skills interfere directly with the effectiveness of the procedure and an analysis of these indicators may reveal opportunities for positive interventions and the improvement of results. Read More →

Cellular regeneration process with porcine skin does not present risks of immunological rejection

Photo: Piece of pork skin, irregular shape similar to a rectangle, sort of yellowish.

Results of the analyzed protocol indicate the viability of the biomaterial for application in regenerative medicine, reducing incompatibility problems in graft and transplant recipients. Aspect and quality of the material obtained provided positive results in cell culture and proliferation, but the decellularization process still needs optimization to minimize hydrogel cytotoxicity. Read More →

Epidemiology and risk factors of hypoglycemia in type 1 diabetes in Brazil

Photo or composition. A cell phone and a blood glucose meter kit (two cylindrical objects, a round jar and the monitor with two buttons). Solid orange background.

Factors associated with hypoglycemia and severe hypoglycemia (SH) in individuals with type 1 diabetes mellitus (T1D) in Brazil shows that avoiding high doses of basal insulin and educating individuals about alcohol consumption and its consequence on glycemic control are simple measures that can contribute to reducing SH events. Read More →

Optical instrument helps monitor survival rate of patients undergoing liver transplant

Close-up photo of a surgery. One hand holds a cylindrical instrument similar to a thick needle, it has a thread at the top end. Another hand holds a pair of scissors. Both instruments are aimed at an opening in a person's body.

Fluorescence spectroscopy under violet light is a minimally invasive optical technique in liver transplant procedures. It demonstrated effectiveness as a complementary tool for monitoring liver grafts in cold perfusion, providing objective information to support the surgeons’ final decision regarding the use of organs for transplantation. Read More →

Trabecular bone score and its evolving role in the assessment and management of clinical conditions

Photo: illustration of a spine in gray tones on a cardboard paper. Below a wooden board. In the background, illustrations on butcher paper in different sheets spread over a surface (hand bones, skull, foot bones).

Trabecular bone score (TBS) is a noninvasive measure of bone quality. A low TBS indicates degraded bone microarchitecture, predicts osteoporotic fracture, and is partially independent of clinical risk factors and bone mineral density. Today TBS has an evolving role in the assessment and management of several clinical conditions. Read More →

Cameras and monitors improves experimental surgeries for correcting incisional hernia in rats

Horizontal rectangular photo. An oval cut in the skin of a mouse. It is possible to see inside the opening a mesh reminiscent of metal, the skin cut around the cut is red and almost translucent, the pinkish skin of the mouse with small spots and some white hairs around the part shaved for the cut. Surrounding the image is an opaque blue background.

The use of cameras and screens in surgical procedures with Wistar rats has demonstrated efficacy and high performance. The 50x magnified visualization with a low-cost system circumvents one of the main difficulties of experimental studies, enabling further research with biocompatible models that generate more accurate results. Read More →

More benefits, fewer risks: Tranexamic acid reduces bleeding and prevents complications in laparoscopic bariatric surgery

Flowchart of the patient analysis in English. At recruitment, starting from the total number of patients (62), 1 was excluded, 0 did not meet the criteria, 0 refused to participate. Allocation: starting from "Control - non-randomized (61)" comes out two arrows forming two horizontal columns. First column: allocated to control group (31), received tranexamic acid (0), follow-up (31), analysis (31). Second column allocated to the group that received tranexamic acid (30), received tranexamic acid (30), follow-up (30), analysis (30).

Medicine’s accessibility, easy administration protocol and absence of thrombogenic adversities indicate that tranexamic acid is a safe and low-cost strategy, applicable to all phases of laparoscopic sleeve gastrectomy surgery, optimizing recovery and reducing hospital stay of patients. Read More →