Category: Health Sciences

Treatment of difficult-to-heal venous ulcers with fibrin sealant

Difficult-to-heal ulcers in lower limbs are those that occur below the knee and for several reasons do not reach healing, remaining open for months or years. Difficulties in healing encourage the development of new products. Fibrin sealant is one of these alternatives because it is a biological dressing with excellent healing properties. Read More →

Bufotenine and new perspectives for the treatment of rabies

Currently, rabies remains almost 100% fatal due to the lack of specific treatment. Bufotenine – an alkaloid present in some frogs’ skin secretions as well as in plant seeds – has been shown to be effective in reducing either the onset of symptoms or the mortality in mice. Read More →

How can the use of a biological glue allow motor recovery after spinal cord injury?

Upper and lower limb injuries are common outcomes of accidents. There is no significant recovery and surgical options are quite limited. A research has developed a new therapy by using the fibrina sealant produced by the Center for the Study of Venoms and Venomous Animals (CEVAP) conjugated with the drug dimethyl fumarate. The results are encouraging regarding mobility recovery. Read More →

Face masks: how important are they in a pandemic?

The use of homemade fabric face mask constitutes an important non-pharmacological intervention to protect population against infection by bacteria and viruses, especially in a pandemic situation. This intervention combined with hygiene, disinfection of high-touch surfaces, and cough etiquettes are efficient measures to prevent transmission of coronavirus. Read More →

Chondroitin Polymerizing Factor and its therapeutic function for the clinical treatment of lung cancer

Lung cancer is the most common malignancy worldwide and is characterized by rapid progression, aggressive behavior, frequent recurrence, and poor prognosis. Study investigate the function of CHPF in lung cancer, lentiviral vectors expressing CHPF shRNA were stably transduced into A549 and H1299 cells. Compared to shCtrl cells, CHPF knockdown cells had significantly reduced proliferation. Read More →

Health professionals fighting COVID-19 in hospitals and risking their health and life to care of infected patients

The paper discusses the challenge faced by health professionals delivering care to patients with COVID-19, and who are at high risk for infection. The adequate use of personal protective equipment reduces the risk, however, there is a need to have adequate provision of these protective materials available, and also trained professionals who can use them. Read More →

Coronavirus Sars-Cov-2 responsible for the COVID-19 pandemic is a specialist in infecting humans

ACE2 is the protein used by new coronavirus (SARS-CoV-2) to enter the host-cells. Our comparative analysis with 70 mammals revealed a relatively high diversity of ACE2 between these species, but no polymorphism within human populations, at least considering 30 sites located at the ACE2 binding sites to the SARS-CoV-2. SARS-CoV-2 can infect any human from any population, but it is unable to infect, naturally and easily, other mammals, including pets. Read More →

Therapeutic toy helps children coping with fear and venous puncture-related pain

This study proposed the use of the therapeutic toy for hospitalized children undergoing venous puncture, and confirmed that this is a valuable resource for children to cope with pain and fear in medical procedures that often generate stress and suffering. Read More →

A traffic educational program for children can help prevent accidents?

A study evaluated the knowledge, attitudes, and preventive practices regarding traffic accidents among children from two public schools in Northeastern Brazil, before and after an educational program created in partnership with a school in Coimbra, Portugal. The educative intervention increased the level of knowledge and maintained the attitudes and preventive practices related to traffic accidents stable among 3rd and 5th grade students. Read More →

Excess body weight and adolescence: what factors are involved?

What are the factors that contribute for excess body weight in adolescents? This study included 635 adolescents from public state schools. The investigation was carried out by researchers from the Universidade Estadual de Monte Claros. Results were quite uncommon considering those often found in studies about excess body weight in adolescents. Read More →