Category: Aem

Pregnant women treated with continuous subcutaneous insulin infusion have better glycemic control

Photograph of a pregnant woman with hands on her belly.

In a comparison of maternal-fetal outcomes among T1D patients treated with continuous subcutaneous insulin infusion (CSII) or multiple daily injections during pregnancy, a higher frequency of cesarean and a lower occurrence of congenital malformations group were observed in the CSII. Adjusted results might indicate that these are influenced by glycemic control. Read More →

Central fat accumulation in women with polycystic ovary syndrome evaluated by different methods

Stock photo. A person wears a tape measure around her body. She is wearing a beige underwear.

In women with polycystic ovary syndrome and normal body mass index, both dual-energy X-ray absorptiometry and the adiposity indices, visceral adiposity index and lipid accumulation product, are the most sensitive methods to evaluate total body fat and fat accumulation in the central abdominal region. Read More →

Stratifying hypoechogenicity into 3 degrees improves ultrasound thyroid nodule risk stratification

Collage of four ultrasound images. Arrows point to the hypoechoic nodules in different degrees.

The analysis of different degrees of hypoechogenicity in thyroid nodules shows that the classification into three grades (mild, moderate, and severe) allows for better differentiation between benign and malignant nodules. The method can avoid unnecessary invasive procedures, in addition to improving efficiency and accuracy in the evaluation of thyroid nodules. Read More →

Serum magnesium concentrations one day after total thyroidectomy are predictors for calcium replacement

Graph. Receiver Operating Characteristic (ROC) curve for the magnesium concentration in the first postoperative day as a predictor of the need for calcium replacement.

The ability of serum magnesium (Mg) (measured on the first postoperative day; Mg1PO) to predict the need for calcium (Ca) replacement, was assessed in patients undergoing total thyroidectomy (TT). In this group of subjects, serum Mg1PO was identified as the isolated predictor for the need for Ca replacement. Read More →

Predictive factors for permanent congenital hypothyroidism was shown by a real-life study in Brazil

Photo: A doctor is holding a baby on an office table. She is smiling and looking at the baby. Baby looks at the camera and seems to bite a finger.

Congenital hypothyroidism can be permanent (PCH) or transient. A real-life retrospective trial aimed to determine predictive factors for PCH and verify its prevalence changes over time. It discovered the most important PCH predictors are the initial thyroid-stimulating hormone serum (TSH) and the blood spot TSH. Read More →

Homeostasis model assessment is negatively associated with the clamp-derived insulin sensitivity index in adolescents

Photo: a hand holding a glucose meter and pointing to a finger of the other hand. In the background, a glucose monitor.

The increase in the prevalence of type 2 diabetes and metabolic syndrome in children and adolescents is a health concern. Therefore, a valid and accessible method of assessing insulin resistance in this age group must be developed to monitor its progression and identifying adolescents at risk of developing associated factors. Read More →

Epidemiology and risk factors of hypoglycemia in type 1 diabetes in Brazil

Photo or composition. A cell phone and a blood glucose meter kit (two cylindrical objects, a round jar and the monitor with two buttons). Solid orange background.

Factors associated with hypoglycemia and severe hypoglycemia (SH) in individuals with type 1 diabetes mellitus (T1D) in Brazil shows that avoiding high doses of basal insulin and educating individuals about alcohol consumption and its consequence on glycemic control are simple measures that can contribute to reducing SH events. Read More →

Trabecular bone score and its evolving role in the assessment and management of clinical conditions

Photo: illustration of a spine in gray tones on a cardboard paper. Below a wooden board. In the background, illustrations on butcher paper in different sheets spread over a surface (hand bones, skull, foot bones).

Trabecular bone score (TBS) is a noninvasive measure of bone quality. A low TBS indicates degraded bone microarchitecture, predicts osteoporotic fracture, and is partially independent of clinical risk factors and bone mineral density. Today TBS has an evolving role in the assessment and management of several clinical conditions. Read More →

InsulinAPP application is effective and safe for the management of hyperglycemia on a hospitalist-managed ward

Imagem retangular na horizontal. Uma mão segurando um celular e a outra mão apontando para a tela. Na tela do celular um gradiente azul. No fundo círculos brancos e linhas tracejadas coloridas (azul, verde, amarelo, laranja, vermelho).

This retrospective study assessed metrics related to inpatient glycemic control using InsulinAPP, an application available for free in Brazil, on the hospitalist-managed ward of a local institution. The results indicated that the InsulinAPP using human insulin formulations was effective and safe for the management of hyperglycemia in this setting. Read More →

Sarcopenia prevalence did not increase in women undergoing gastric bypass despite weight loss

Graphic with number of patients with sarcopenia parameters in the bariatric and control groups (A) and in bariatric and control groups based on sarcopenia diagnosis (B)

Women (18-65 years old) who underwent bariatric surgery (BG) ≥ 2 years and reached stable weight ≥ 6 months, were investigated in an observational, cross-sectional study for sarcopenia’s presence. Patients subjected to Roux-en-Y gastric bypass did not show increased sarcopenia prevalence in comparison to non-operated women with obesity, despite the significant weight loss. Read More →