In an evaluation of the colon tissue of rats with induced ulcerative colitis, the use of curcumin, a substance present in turmeric, contributed to the reduction of the inflammatory process. The results reveal an optimistic outlook for the application of curcumin and its potential as a pharmaceutical product. … Read More →
Substance present in turmeric may be a new therapeutic option in the treatment of ulcerative colitis
Sarcopenia prevalence did not increase in women undergoing gastric bypass despite weight loss
Women (18-65 years old) who underwent bariatric surgery (BG) ≥ 2 years and reached stable weight ≥ 6 months, were investigated in an observational, cross-sectional study for sarcopenia’s presence. Patients subjected to Roux-en-Y gastric bypass did not show increased sarcopenia prevalence in comparison to non-operated women with obesity, despite the significant weight loss. … Read More →
Sequencing of the first case of the monkeypox virus in Brazil
Monkeypox virus, a zoonotic virus endemic to the African continent, has been reported in 33 non-endemic countries since May 2022. We report an almost complete genome of the first confirmed case of MPXV in Brazil. Shotgun metagenomic sequencing was completed in 18 hours, from DNA extraction to consensus sequence generation. … Read More →
Impact of semioccluded vocal tract exercises and choral singing in congenital GH deficiency’s subjects
Isolated growth hormone deficiency (IGHD) individuals report normal general quality of life but rate their Voice-Related Quality of Life (V-RQOL) as low. Voice therapy with semioccluded vocal tract exercises and choral training can markedly improve V-RQOL scores, voice self-assessment and auditory-perceptual analysis in IGHD subjects, although GH replacement therapy is not widely accepted. … Read More →
Expanding the horizons of medical science in fighting portal hypertension with mini pigs
In search of new alternatives for the treatment of portal hypertension, a model validation in medium-sized animals was performed, allowing the improvement of techniques applied in cases of gastrointestinal hemorrhage and indicating the direction for advances in diagnostic and therapeutic procedures that aim to cure diseases and save lives. … Read More →
Brazilian Medical Societies propose a new obesity classification based on weight history
In the new obesity classification, individuals losing a specific proportion of weight are classified as having “reduced” or “controlled” obesity. This classification could help disseminate the concept of clinical benefits derived from modest weight loss, allowing subjects with obesity and their health care professionals to focus on strategies for weight maintenance instead of further weight reduction. … Read More →
Canagliflozin seems to be more potent in reducing glycated hemoglobinand and body weight in patients with type 2 diabetes
Among the different doses of gliflozins commercially available in Brazil, Canagliflozin 300 mg had the greatest benefit in terms of body weight reduction, however, results were not different from empagliflozin 25 mg and dapagliflozin 10 mg. It’s not worthwhile to increase gliflozins doses with the intent to further decrease glycated hemoglobin or body weight. … Read More →
COVID-19 Affects Perioperative Morbidity and Mortality in Patients Requiring Cardiovascular Surgery
A retrospective Brazilian multicenter cohort study with 104 patients investigated how COVID-19 affects the perioperative period of cardiovascular surgery. Patients with a positive RT-PCR test within ten days before or after surgery and those presenting with positive RT-PCR test > 10 days after surgery showed significantly higher postoperative complications and death. … Read More →
The prognosis of differentiated thyroid cancer is not affected by pregnancy
Pregnancy had no impact on the natural course of differentiated thyroid cancer. Disease progression after pregnancy was limited and probably related to more aggressive disease and higher risk stratification at diagnosis. Still, mild disease progression may have occurred asymptomatically in some patients. … Read More →
Multifocality and LN metastasis are independent risk factors for incomplete response in TMC patients
This was a retrospective study that aimed at identifying possible risk factors associated with an incomplete response to therapy in thyroid microcarcinoma (TMC) treated with total thyroidectomy, with or without radioactive iodine (RAI) therapy, reclassified according to the response to treatment into “favorable” (excellent/indeterminate) or “unfavorable” (biochemical/structural incomplete) responses. … Read More →
Recent Comments