Author: Daniela Barros

The estimated budget impact of adding cabergoline to the formulary for Cushing’s disease (CD) treatment within the Brazilian Public Health System would be about BRL $6 million. While cost savings cannot be expected, the budget impact of adding cabergoline would be lower than that of adding other treatment options. … Read More →

When comparing long-term medical costs of active surveillance (AS), partial thyroidectomy, and total thyroidectomy in patients with low-risk papillary thyroid microcarcinoma that receives care covered by their Public Health System, researchers concluded that the AS approach was less costly than immediate surgery over a 30-year follow-up period. … Read More →

In a comparison of maternal-fetal outcomes among T1D patients treated with continuous subcutaneous insulin infusion (CSII) or multiple daily injections during pregnancy, a higher frequency of cesarean and a lower occurrence of congenital malformations group were observed in the CSII. Adjusted results might indicate that these are influenced by glycemic control. … Read More →

In women with polycystic ovary syndrome and normal body mass index, both dual-energy X-ray absorptiometry and the adiposity indices, visceral adiposity index and lipid accumulation product, are the most sensitive methods to evaluate total body fat and fat accumulation in the central abdominal region. … Read More →

The analysis of different degrees of hypoechogenicity in thyroid nodules shows that the classification into three grades (mild, moderate, and severe) allows for better differentiation between benign and malignant nodules. The method can avoid unnecessary invasive procedures, in addition to improving efficiency and accuracy in the evaluation of thyroid nodules. … Read More →

The ability of serum magnesium (Mg) (measured on the first postoperative day; Mg1PO) to predict the need for calcium (Ca) replacement, was assessed in patients undergoing total thyroidectomy (TT). In this group of subjects, serum Mg1PO was identified as the isolated predictor for the need for Ca replacement. … Read More →

Congenital hypothyroidism can be permanent (PCH) or transient. A real-life retrospective trial aimed to determine predictive factors for PCH and verify its prevalence changes over time. It discovered the most important PCH predictors are the initial thyroid-stimulating hormone serum (TSH) and the blood spot TSH. … Read More →

The increase in the prevalence of type 2 diabetes and metabolic syndrome in children and adolescents is a health concern. Therefore, a valid and accessible method of assessing insulin resistance in this age group must be developed to monitor its progression and identifying adolescents at risk of developing associated factors. … Read More →

Factors associated with hypoglycemia and severe hypoglycemia (SH) in individuals with type 1 diabetes mellitus (T1D) in Brazil shows that avoiding high doses of basal insulin and educating individuals about alcohol consumption and its consequence on glycemic control are simple measures that can contribute to reducing SH events. … Read More →

Trabecular bone score (TBS) is a noninvasive measure of bone quality. A low TBS indicates degraded bone microarchitecture, predicts osteoporotic fracture, and is partially independent of clinical risk factors and bone mineral density. Today TBS has an evolving role in the assessment and management of several clinical conditions. … Read More →